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- PubMed Central (PMC)https://pmc.ncbi.nlm.nih.gov/articles/PMC2621399/Treatment of hereditary angioedema with plasma-derived C1 inhibitorBased on over 20 years of data, including recently completed double-blind, placebo-controlled trials, C1-INH concentrate appears to be very effective in the ...
- KalVista Pharmaceuticalshttps://ir.kalvista.com/news-releases/news-release-details/kalvista-pharmaceuticals-presents-kvd900-data-c1-inhibitorKalVista Pharmaceuticals Presents KVD900 Data at C1-Inhibitor ...May 28, 2019 ... The Company has selected KVD900 as its program to be advanced as an on-demand therapy for HAE attacks and commenced a Phase 2 proof-of-concept ...
- PubMed Central (PMC)https://pmc.ncbi.nlm.nih.gov/articles/PMC3666183/Hereditary Angioedema Caused By C1-Esterase Inhibitor Deficiency ...Therefore, prophylactic therapy is an integral part of HAE treatment in the United States and for selected patients worldwide. Routine long-term prophylaxis ...
- https://medlineplus.gov/druginfo/meds/a622016.htmlC1-Esterase Inhibitor Human Injection: MedlinePlus Drug InformationMar 15, 2022 ... C1-esterase inhibitor human injection (Berinert) is used to treat acute attacks of hereditary angioedema in adults and children who have ...
- PubMed Central (PMC)https://pmc.ncbi.nlm.nih.gov/articles/PMC9510393/Treatment of hereditary angioedema—single or multiple pathways to ...In addition to C1-INH replacement therapy, the plasma kallikrein inhibitors lanadelumab and berotralstat are recommended as first-line options for long-term ...
- https://www.mp.pl/paim/issue/article/15138/Bradykinin and oxidative stress in patients with hereditary ...Jan 14, 2020 ... Hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE) is a rare hereditary disease, in which the deficiency of C1 inhibitor disturbs ...
- https://link.springer.com/article/10.1007/s40629-018-0088-5Guideline: Hereditary angioedema due to C1 inhibitor deficiency ...Jan 17, 2019 ... Treatment of laryngeal edema in the setting of HAE-C1-INH depends on how advanced laryngeal edema is. In the case of life-threatening ...
- The New England Journal of Medicinehttps://www.nejm.org/doi/full/10.1056/NEJMoa0805538Nanofiltered C1 Inhibitor Concentrate for Treatment of Hereditary ...Aug 5, 2010 ... Hereditary angioedema due to C1 inhibitor deficiency is characterized by recurrent acute attacks of swelling that can be painful and ...
- Annals of Allergy, Asthma & Immunologyhttps://www.annallergy.org/article/S1081-1206(18)30611-2/fulltextLong-term prophylaxis therapy in patients with hereditary ...Treatment guidelines for long-term prophylaxis therapy of patients with hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) have changed over time ...
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10287105/Management of hereditary angioedema in resource-constrained ...Jun 6, 2023 ... Replacement of plasma-derived or recombinant C1-esterase inhibitor (C1-INH) protein, administered intravenously, is the treatment of choice ...
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